Who We Are

Global Collaboration

A Global Collaboration

Mom Genes Fight PPD (previously called PPD Act) is a research study developed by Postpartum Depression: Action Towards Causes and Treatment (PACT) Consortium, an international group of academic clinicians and scientists committed to understanding the interaction of genes and environment to predict which women are at risk of postpartum depression (PPD).

Teams on the Project

Researchers in the Departments of Psychiatry and Genetics at the University of North Carolina at Chapel Hill who are PACT Consortium members are leading Mom Genes Fight PPD and overseeing the US arm of the study. Researchers from Queensland Brain Institute at the University of Queensland, and University of Toronto oversee the Australian and Canadian arms of the study. Researchers from the National Centre for Mental Health at Cardiff University and Aarhus University will launch the study in the UK and Denmark in the future.

PACT United States

Jerry Guintivano

Jerry Guintivano

Holly Krohn

Holly Krohn

PACT Australia

The PACT Australia team is composed of several different institutions, including Naomi Wray and the team at Queensland.

Bernhard Baune

Bernhard Baune

Anne Buist

Anne Buist

Enda Byne

Enda Byne

Ian Hickie

Ian Hickie

Julio Licinio

Julio Licinio

Nick Martin

Nick Martin

Jeannette Milgrom

Jeannette Milgrom

Naomi Wray

Naomi Wray

The Australian arm collects more detailed information about health and lifestyle as part of the Genetics of Risk and Response to Treatment of Depression study.

PACT Canada

The PACT Canada team is comprised of contributors from institutions across Canada, and is being led by Dr. Simone Vigod and her team from Women's College Hospital at the University of Toronto, in Toronto, Ontario. PACT Canada gratefully acknowledges funding from the Women's Mental Health Program at Women's College Hospital for the launch of the PACT Canada pilot study of the PACT app.

Dr. Simone Vigod

Dr. Simone Vigod, Lead Investigator | Women's College Hospital and University of Toronto

Dr. James L. Kennedy

Dr. James L. Kennedy | Centre for Addiction and Mental Health & University of Toronto

Dr. Valerie Taylor

Dr. Valerie Taylor | Women's College Hospital & University of Toronto

Dr. Cindy-Lee Dennis

Dr. Cindy-Lee Dennis | St. Michael's Hospital & University of Toronto

Dr. Sophie Grigoriadi

Dr. Sophie Grigoriadis | Sunnybrook Health Sciences Centre & Univeristy of Toronto

Dr. Tim Oberlander

Dr. Tim Oberlander | BC Children's Hospital and BC Women's Hospital and Health Centre & University of British Columbia

Dr. Benicio N. Frey

Dr. Benicio N. Frey | St. Joseph's Healthcare & McMaster University

r. Ryan Van Lieshout

Dr. Ryan Van Lieshout | St. Joseph's Healthcare & McMaster University

The PACT Canada team also gratefully acknowledges the research personnel supporting the development of this project, including Ms. Neesha Hussain-Shamsy and Dr. Kennedy's Research Team at the Psychiatric Neurogenetics Laboratory and Tanenbaum Centre for Pharmacogenetics at the Centre for Addiction and Mental Health.

PACT United Kingdom

The PACT UK team is associated with National Centre for Mental Health and Cardiff University.

PACT Denmark

The PACT Denmark team is associated with National Center for Register-Based Research, Aarhus University.

Sponsors

UNC

The UNC School of Medicine Departments of Psychiatry and Genetics sponsored the creation of the app. Within the UNC Department of Psychiatry, The team from UNC Center for Women's Mood Disorders provided the infrastructure to create the app. The UNC Center for Health Innovation provided critical project management.

NIH

The National Institute of Mental Health (NIMH) is the lead federal agency for research on mental disorder focused on transforming the understanding and treatment of mental illnesses through basic and clinical research, paving the way for prevention, recovery, and cure. NIMH is partnering with PPD ACT to provide the spit kits used for DNA collection.

PSI

Postpartum Support International was founded in 1987 by Jane Honikman in Santa Barbara, California. The purpose of the organization is to increase awareness among public and professional communities about the emotional changes that women experience during pregnancy and postpartum. Approximately 15% of all women will experience postpartum depression following the birth of a child. Up to 10% will experience depression or anxiety during pregnancy. When the mental health of the mother is compromised, it affects the entire family.

Sage

SAGE Therapeutics is a neuroscience-focused company discovering medicines to treat life-threatening, rare CNS disorders. Launched in 2010, SAGE is a publicly traded company led by an experienced team of leaders, CNS experts and investors. Our lead program, SAGE-547, is in clinical development for super-refractory status epilepticus (SRSE) and is the first of many in an exciting portfolio of potential seizure medicines.

Foundation of Hope

The Foundation of Hope promotes scientific research aimed at discovering the causes and potential cures for mental illness in order to develop a more effective means of treatment. The Foundation is committed to raising community awareness and supporting effective treatment programs. The Foundation provides financial support for ongoing and new research and treatment, as well as the development of researchers at the University of North Carolina at Chapel Hill, its affiliated psychiatric institutions, and local mental health agencies.

PACT Members

Margaret Altemus
Weill Cornell Medical College, Department of Psychiatry, US
Robert Ammerman
University of Cincinatti, US
Gisele Apter
Erasme Hospital, Paris Diderot University, France
Geena Athappilly
Brigham and Women's Hospital, Harvard Medical School, US
Jehannine C. Austin
Departments of Psychiatry and Medical Genetics, University of British Columbia, Vancouver, Canada
Bernhard T. Baune
Discipline of Psychiatry, University of Adelaide, Australia
Veerle Bergink
Erasmus MC, Department of Psychiatry/Psychology, Rotterdam, The Netherlands
Justin Bilzta
University of Melbourne, Women's Mental Health, Australia
Rebecca Brock
The University of Iowa, Department of Psychology, US
Anne Buist
University of Melbourne, Women's Mental Health, Australia
Nancy Byatt
DO, Psychiatry, University of Massachusetts, US
Enda Byrne
Queensland Brain Institute, University of Queensland, Australia
Kristina Deligiannidis
Zucker Hillside Hospital, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, US
Cindy Lee-Dennis
University of Toronto, Centre for Addiction and Mental Health, Canada
Emmanuel Devouche
Erasme Hospital, Paris Descartes University, France
Arianna Di Florio
The University of North Carolina at Chapel Hill, US and Cardiff University, UK
C. Neill Epperson
University of Pennsylvania, Department of Psychiatry, US
Benicio Frey
St. Josephs Healthcare Hamilton, McMaster University, Canada
Sophie Grigoriadis
University of Toronto, Department of Psychiatry, Sunnybrook Health Sciences Centre, Canada
Constance Guille
Medical University of South Carolina, Department of Psychiatry, US
Jerry Guintivano
The University of North Carolina at Chapel Hill, Department of Psychiatry, US
Katja Ingstrup
Aarhus University, Department of Economics & Business Economics, Denmark
Hadine Joffe
Brigham and Women's Hospital, Harvard Medical School, US
Ian Jones
Cardiff University School of Medicine, Institute of Psychological Medicine and Clinical Neuroscience, UK
James L. Kennedy
Centre for Addiction and Mental Health, University of Toronto, Canada
Deborah Kim
University of Pennsylvania, Department of Psychiatry, US
Paul Lichtenstein
Karolinska Institute, Department of Medical Epidemiology and Biostatistics, Sweden
Patrik Magnusson
Karolinska Institute, Department of Medical Epidemiology and Biostatistics, Sweden
Pedro Martinez
National Institute of Mental Health, NIH, US
Samantha Meltzer-Brody
The University of North Carolina at Chapel Hill, Department of Psychiatry, US
Jeannette Milgrom
University of Melbourne, Australia
Catherine Monk
Departments of Obstetrics and Gynecology, and Psychiatry, Columbia University, New York
Trine Munk-Olsen
Aarhus University, Department of Economics and Business (NCRR), Denmark
Maria Muzik
Department of Psychiatry, University of Michigan, US
Jeff Newport
University of Miami, Department of Psychiatry, US
Tim Oberlander
BC Children's and Women's Health Centre of British Columbia, Canada
Michael O'Hara
The University of Iowa, Department of Psychology, US
Jennifer Payne
The Johns Hopkins University, Department of Psychiatry, US
Brenda Penninx
VU University Medical Center, Department of Psychiatry, The Netherlands
Karen Putnam
The University of North Carolina at Chapel Hill, Department of Psychiatry, US
Natalie Rasgon
Department of Psychiatry, Stanford University, US
Thalia Robakis, MD
Department of Psychiatry, Stanford University, US
Emma Robertson-Blackmorek
University of Florida at Jacksonville, Department of Psychiatry, US
Sabine Roza
Erasmus MC, Department of Psychiatry/Psychology, Rotterdam, The Netherlands
David Rubinow
The University of North Carolina at Chapel Hill, Department of Psychiatry, US
Peter Schmidt
National Institute of Mental Health, NIH, US
Katherine Sharkey
Alpert Medical School of Brown University/Rhode Island Hospital, Department of Psychiatry, US
Tiffany Moore Simas
Obstretrics and Gynecology, University of Massachusetts, US
Meir Steiner
Professor Emeritus, Department of Psychiatry, McMaster University, Canada
Zach Stowe
University of Arkansas for Medical Sciences, Department of Psychiatry, US
Scott Stuart
The University of Iowa, Department of Psychology, US
Patrick Sullivan
The University of North Carolina at Chapel Hill, Department of Psychiatry, US
Valerie Taylor
Women's College Research Institute, Women's College Hospital, Department of Medicine, Canada
Henning Tiemeier
Erasmus MC, Department of Psychiatry/Psychology, Rotterdam, The Netherlands
Ryan Van Lieshout
St. Josephs Healthcare Hamilton,McMaster University, Canada
Simone Vigod
Women's College Hospital, Department of Psychiatry, University of Toronto, Canada
Alexander Vikorin
Karolinska Institute, Department of Medical Epidemiology and Biostatistics, Sweden
Katherine Wisner
Northwestern University Feinberg School of Medicine, Asher Center for the Study and Treatment of Depressive Disorders, US
Naomi Wray
University of Queensland, Australia

Developers

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PSI

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